The Checkup With Dr. David Agus (2026)

Oprah Winfrey and Maria Shriver discuss their experiences with "the Big M," aiming to bring light to the physical and emotional changes of menopause.

Amy Schumer opens up about her lifelong battle with the "lonely disease," including her decision to undergo a hysterectomy. The Checkup with Dr. David Agus

Nick Cannon shares the devastating experience of losing his five-month-old son, Zen, to brain cancer. Oprah Winfrey and Maria Shriver discuss their experiences

The show is noted for its candid approach to medical issues that are often stigmatized or kept private: The Checkup with Dr. David Agus