SNC1 is part of the RPP5 locus, a cluster of paralogous disease resistance (R) genes that allows the plant to adapt to pathogens. 4. Summary Table: SNC1 Characteristics Description Protein Type TIR-NB-LRR (NLR) Immune Receptor Model Organism Arabidopsis thaliana (Col-0) Key Action Activates effector-triggered immunity Mutant Phenotype Constitutive activation (dwarfism) Interacting Partner TPR1 (Transcriptional corepressor)
SNC1 forms a complex with Topless-related 1 (TPR1) to repress negative regulators of immunity (DND1 and DND2), thus boosting plant defenses. SnC1.rar
The snc1-1 mutant is a gain-of-function mutant, leading to constitutive (continuous) defense responses and a dwarf phenotype. SNC1 is part of the RPP5 locus, a