It is Liz's 31st birthday (though some sources note a discrepancy where she might be turning 30). Red gives her a bottle of wine made from grapes she once harvested with her adoptive father, Sam, highlighting his long-standing presence in her life.
Red eventually tracks down Powell, hoping the doctor can help recover Liz's lost memories of the fire. However, Powell admits his research failed, and he commits suicide in front of Red. Personal Storylines [S2E17] The Longevity Initiative
Powell isn't actually trying to discover immortality for Hobbs. Instead, he is using the billionaire's funding for his own goal: restoring the memories and cognitive functions of his fiancée, who suffered severe brain damage in a car accident he caused. It is Liz's 31st birthday (though some sources