Quabain May 2026

: This sodium buildup forces the cell to retain more calcium. In heart muscle cells, this extra calcium strengthens contractions.

: Conversely, abnormally high levels of endogenous ouabain are linked to chronic high blood pressure and heart failure. QUABAIN

: It is extracted from the seeds of Strophanthus gratus and the bark of the Acocanthera ouabaio tree. : This sodium buildup forces the cell to retain more calcium

While once thought to be exclusively plant-based, scientists discovered that humans and other mammals produce an version of ouabain. : It is extracted from the seeds of

: It binds to and stops the pump, causing sodium to build up inside the cell.

: High doses have shown an ability to inhibit the growth of certain tumor cells, including thyroid and lung cancers.

(pronounced WAH-bane ), also known as g-strophanthin , is a potent cardiac glycoside and steroid hormone naturally found in both African plants and mammals. Historically used by African hunters as an arrow poison due to its rapid effect on the heart, it is now primarily used as a research tool for studying cell signaling and, in some countries, as a medication for heart conditions. How it Works: The Na+/K+-ATPase Pump