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Napoli reached their first-ever UCL quarter-final with a 2-0 away win and a 3-0 home win . Frankfurt 2-0 (Agg)
: Napoli was notably without injured star midfielder Kevin De Bruyne , which hampered their creative output in the final third .
The two sides most recently met at the Stadio Diego Armando Maradona in the Champions League league phase , resulting in a .
The recent history between and Eintracht Frankfurt has shifted from a one-sided Italian dominance in 2023 to a more balanced, defensive struggle in their most recent encounter in November 2025. While Napoli holds the historical upper hand in goals scored, Frankfurt recently demonstrated a renewed defensive resilience. Tue, Nov 4 Eintracht Frankfurt Recent Match Review (November 4, 2025)
: Under manager Antonio Conte , Napoli controlled nearly 70% of possession but struggled with clinical finishing .
Frankfurt won both legs 1-0 to advance to the third round . Napoli 0-0 Frankfurt (Nov 4, 2025) Game Analysis - ESPN