An excessive leak of ACh causes localized muscle fibers to stay in a state of permanent contraction.
Clinical diagnosis relies primarily on manual palpation by a skilled therapist or physician. Key features include: Myofascial Trigger Points: Pathophysiology and ...
Myofascial Trigger Points Then and Now: A Historical ... - PMC An excessive leak of ACh causes localized muscle
The resulting "energy crisis" triggers the release of inflammatory substances like bradykinin, serotonin, and substance P. These chemicals sensitize local pain receptors, creating the characteristic "exquisite tenderness" and referred pain. 2. Identifying the "Knot" Myofascial Trigger Points: Pathophysiology and ...