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Covers nucleic acid extraction methods, electrophoresis, hybridization technologies, restriction enzyme mapping, and amplification techniques (PCR, NASBA).
Molecular Diagnostics: Fundamentals, Methods, & Clinical Applications by Lela Buckingham (and Maribeth L. Flaws in earlier editions) is a leading textbook designed for clinical laboratory science students and professionals, with a new 4th edition published in February 2026. It provides a foundational understanding of nucleic acid biochemistry, common laboratory techniques, and the clinical application of molecular-based assays. Core Areas Covered Molecular Diagnostics: Fundamentals, Methods, &...
Contains over 300 line drawings and color plates illustrating molecular concepts. Key Techniques Discussed It provides a foundational understanding of nucleic acid
Reviews the structure and function of DNA, RNA, and proteins, covering topics such as replication, transcription, and translation. human identification (forensics/paternity)
Discusses the application of molecular diagnostics to infectious diseases, oncology, human identification (forensics/paternity), and inherited disease diagnosis. Key Features of the Text
Highlights advanced, in-depth material to challenge students.
The textbook is generally organized into three key sections, covering the full spectrum of molecular laboratory practices: