Grey's Anatomy S16e16 Direct

Alex claims that while he still loves Jo , he cannot bear to let his children grow up without a father the way he did. He is now living on a farm in Kansas where Izzie works as a surgical oncologist. ⚡ Secondary Storylines

He expresses his gratitude for their mentorship over the years. The Big Reveal: Izzie Stevens and the Twins Grey's Anatomy s16e16

After reading the letter and realizing her marriage is over, Jo heads back to work, determined to stay strong despite the heartbreak. 🗣️ Fan and Critic Reaction Alex claims that while he still loves Jo

While calling former colleagues to gather support for Meredith’s medical license hearing (earlier in the season), Alex reached out to Izzie . The Big Reveal: Izzie Stevens and the Twins

Izzie has five-year-old twins, Eli and Alexis , who are biologically Alex’s.