Antifungal Agent -

: Caspofungin , micafungin, and anidulafungin. 4. Allylamines

-(1,3)-D-glucan, a major polysaccharide responsible for maintaining the structural integrity of the cell wall, causing cell lysis. antifungal agent

: This class targets the fungal cell wall rather than the membrane. They inhibit the enzyme -(1,3)-D-glucan synthase. Effect : This blocks the synthesis of : Caspofungin , micafungin, and anidulafungin

: Allylamines inhibit the enzyme squalene epoxidase. : This class targets the fungal cell wall

: Blocking this enzyme leads to ergosterol depletion and the accumulation of toxic methylated sterols, ultimately altering membrane function and stopping growth.

To combat fungal infections safely, medical science targets biological structures and pathways that are unique to fungi. Modern antifungal agents are primarily categorized into four major classes based on their specific mechanisms:

: This binding creates physical pores or channels in the membrane. Small essential molecules and cellular organelles leak out of these pores, causing cell death. Common Examples : Amphotericin B, nystatin , and natamycin. 3. Echinocandins